NIST Special Publication (SP) 800-171 consists of 110 requirements that cover various areas of an organization’s IT technology, policy, and practices. These requirements are crucial for safeguarding Controlled Unclassified Information (CUI) within systems. Let’s delve into some of the key areas covered by these requirements:

1. Access Control: Implement controls to restrict access to authorized users.
2. Awareness and Training: Ensure personnel are educated about security practices.
3. Audit and Accountability: Maintain audit logs and track system activity.
4. Configuration Management: Manage system configurations securely.
5. Identification and Authentication: Verify user identities.
6. Maintenance: Regularly update and maintain systems.
7. Media Protection: Protect physical and digital media containing CUI.
8. Physical and Environmental Protection: Safeguard physical assets.
9. Personnel Security: Screen and manage personnel access.
10. System and Communications Protection: Secure communication channels.
11. System and Information Integrity: Detect and prevent unauthorized changes.

These requirements are essential for minimizing security risks and ensuring the confidentiality of CUI across various business environments. For the complete list, you can refer to the authoritative source in SP 800-171 Rev. 2, Protecting Controlled Unclassified Information in Nonfederal Systems and Organizations | CSRC (nist.gov)